Publications

UNIT of Cell Physiology and Nutrition

Islet Cell Signaling

Regulation of a, ß and d-Cells

Human Nutrition

ARTICLES

Last 5 years
  1. Nuñez P, Fernandez T, García-Arévalo M, Alonso-Magdalena P, Nadal A, Perillan C, Arguelles J.. (2018) Effects of bisphenol A treatment during pregnancy on kidney development in mice: a stereological and histopathological study.. J Dev Orig Health Dis. 9(2):208-214.
  2. Gallo F, Fossi C, Weber R, Santillo D, Sousa J, Ingram I, Nadal A, Romano D.. (2018) Marine litter plastics and microplastics and their toxic chemicals components: the need for urgent preventive measures. Environ Sci Eur. 30(1):13.
  3. Nadal A, Fuentes E, Ripoll C, Villar-Pazos S, Castellano-Muñoz M, Soriano S, Martinez-Pinna J, Quesada I, Alonso-Magdalena P. (2018) Extranuclear-initiated estrogenic actions of endocrine disrupting chemicals: Is there toxicology beyond paracelsus?. J Steroid Biochem Mol Biol. 176:16-22.
  4. Villar-Pazos S, Martinez-Pinna J, Castellano-Muñoz M, Alonso-Magdalena P, Marroqui L, Quesada I, Gustafsson JA, Nadal A.. (2017) Molecular mechanisms involved in the non-monotonic effect of bisphenol-a on Ca2+ entry in mouse pancreatic β-cells. Scientific Reports. 7(1):11770.
  5. Nadal A, Quesada I, Tudurí E, Nogueiras R, Alonso-Magdalena P. (2017) Endocrine-disrupting chemicals and the regulation of energy balance. Nat Rev Endocrinol. 13: 536-546.
  6. Tudurí E, López M, Diéguez C, Nadal A, Nogueiras R. (2017) GPR55 and the regulation of glucose homeostasis. Int J Biochem Cell Biol. 88: 204-207.
  7. Mimoto MS, Nadal A, Sargis RM. (2017) Polluted Pathways: Mechanisms of Metabolic Disruption by Endocrine Disrupting Chemicals. Curr Environ Health Rep. 4(2):208-222.
  8. Heindel JJ, Blumberg B, Cave M, Machtinger R, Mantovani A, Mendez MA, Nadal A, Palanza P, Panzica G, Sargis R, Vandenberg LN, Saal FV. (2017) Metabolism Disrupting Chemicals and Metabolic Disorders. Reproductive Toxicology. 68:3-33.
  9. Alonso-Magdalena P, Rivera FJ, Guerrero-Bosagna C. (2016) Bisphenol-A and metabolic diseases: epigenetic, developmental and transgenerational basis. Environmental Epigenetics. 2 (3): dvw022.
  10. García-Arévalo M, Alonso-Magdalena P, Servitja JM, Boronat T, Merin B, Villar S, Medina-Gómez G, Novials A, Quesada I, Nadal A. (2016) Maternal exposure to Bisphenol-A during pregnancy increases pancreatic β-cell growth during early life in male mice offspring. Endocrinology. 157:4158-4171.
  11. Tudurí E, López M, Diéguez C, Nadal A, Nogueiras R. (2016) Glucagon-Like Peptide 1 Analogs and their Effects on Pancreatic Islets. Trends in Endocrinology and Metabolism. 27:304-318.
  12. Santos RS, Batista TM, Camargo RL, Morato PN, Borck PC, Leite NC, Kurauti MA, Wanschel AC, Nadal Á, Clegg DJ, Carneiro EM. (2016) Lacking of estradiol reduces insulin exocytosis from pancreatic β-cells and increases hepatic insulin degradation.. Steroids. 114:16-24.
  13. Lind L, Lind PM, Lejonklou MH, Dunder L, Bergman Å, Guerrero-Bosagna C, Lampa E, Lee HK, Legler J, Nadal A, Pak YK, Phipps RP, Vandenberg LN, Zalko D, Ågerstrand M, Öberg M, Blumberg B, Heindel JJ, Birnbaum LS. (2016) Uppsala Consensus Statement on Environmental Contaminants and the Global Obesity Epidemic.. Environ Health Perspect. 124(5):A81-3.
  14. Robledo CA, Romano ME, Alonso-Magdalena P. (2016) Review of Current Evidence on the Impact of Environmental Chemicals on Gestational Diabetes Mellitus. Current Epidemiology Reports. 3:51–62.
  15. Soriano S, Ripoll C, Alonso-Magdalena P, Fuentes E, Quesada I, Nadal A, Martinez-Pinna J. (2016) Effects of Bisphenol A on ion channels: experimental evidence and molecular mechanisms.. Steroids. 111:12-20.
  16. Quesada I. (2016) Pancreatic alpha-cells and insulin-deficient diabetes. Endocrinology. 157:446-448.
  17. Mellado Gil JM, Jiménez-Moreno CM, Martin-Montalvo A, Alvarez-Mercado AI, Cobo-Vuilleumier N, Lorenzo PI, Bru-Tari E, de Gracia Herrera Gómez I, López Noriega L, Pérez Florido J, Santoyo-López J, Spyrantis A, Meda P, Boehm BO, Quesada I., Gauthier BR. (2016) Pax4 Preserves Endoplasmic Reticulum Integrity Preventing Beta-Cell Degeneration In Type 1 Diabetes Mellitus. Diabetologia. 59(4):755-65.
  18. Vettorazzi JF, Ribeiro RA, Borck PC, Souto Branco RC, Soriano S, Merino B, Boschero AC, Angel Nadal, Quesada I.*, Carneiro EM*. (2016) The bile acid TUDCA increases glucose-induced insulin secretion via the cAMP/PKA pathway in the pancreatic Β-cell. Metabolism. 65:54–63.
  19. Gore AC, Chappell VA, Fenton SE, Flaws JA, Nadal A, Prins GS, Toppari J, Zoeller RT. (2015) Executive Summary to EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals. Endocrine Reviews. 36(6):E1-E150.
  20. Merino B, Quesada I, Hernandez-Cascales J. (2015) Glucagon increases beating rate but not contractility in rat right atrium. Comparison with isoproterenol. Plos One. 10: e0132884.
  21. Vieira E, Merino B, Quesada I. (2015) Role of the clock gene Rev-erb alpha in metabolism and in the endocrine pancreas. Diabetes, Obesity and Metabolism. 17 (Suppl. 1): 106-114.
  22. Merino B, Alonso-Magdalena P, Lluesma M, Ñeco P, Gonzalez A, Marroquí L, García-Arévalo M, Nadal A, Quesada I. (2015) Pancreatic alpha-cells from female mice undergo morphofunctional changes during compensatory adaptations of the endocrine pancreas to diet-induced obesity. Scientific Reports. 5:11622.
  23. Santos-Silva JC, Ribeiro RA, Vettorazzi JF, Irles E, Rickli S, Borck PC, Porciuncula PM, Quesada I, Nadal A, Boschero AC, Carneiro EM. (2015) Taurine supplementation ameliorates glucose homeostasis, prevents insulin and glucagon hypersecretion, and controls beta, alpha, and delta-cell masses in genetic obese mice. Amino Acids. 47: 1533-48.
  24. Alonso-Magdalena P, Quesada I, Nadal A. (2015) Prenatal exposure to BPA and offspring outcomes: the diabesogenic behaviour of BPA. Dose-Response. 13: 1559325815590395.
  25. Alonso-Magdalena P, García-Arévalo M, Quesada I, Nadal A. (2015) Bisphenol-A Treatment During Pregnancy in Mice: A New Window of Susceptibility for the Development of Diabetes in Mothers Later in Life. Endocrinology. 156: 1659–1670.
  26. Marroqui L, Masini M, Merino B, Grieco FA, Millard I, Dubois C, Quesada I, Marchetti P, Cnop M, Eizirik DL. (2015) Pancreatic Alpha Cells are Resistant to Metabolic Stress-induced Apoptosis in Type 2 Diabetes. EBiomedicine. 2: 378-385.
  27. Irles E, Ñeco P, Lluesma M, Villar-Pazos S, Santos-Silva JC, Vettorazzi JF, Alonso-Magdalena P, Carneiro EM, Boschero AC, Nadal Á, Quesada I. (2015) Enhanced glucose-induced intracellular signaling promotes insulin hypersecretion: Pancreatic beta-cell functional adaptations in a model of genetic obesity and prediabetes. Molecular and Cellular Endocrinology. 404:46-55.
  28. Vieira E, Burris TP, Quesada I. (2014) Clock genes, pancreatic function and diabetes. Trends in Molecular Medicine. 20:685-693.
  29. Rafacho A, Ortsäter H, Nadal A, Quesada I. (2014) Glucocorticoid treatment and endocrine pancreas function: implications for glucose homeostasis, insulin resistance and diabetes. Journal of Endocrinology. 223:R49-R62.
  30. Saavedra-Ávila NA, Sengupta U, Sánchez B, Sala E, Haba L, Stratmann T, Verdaguer J, Mauricio D, Mezquita B, Ropero AB, Nadal A, Mora C. (2014) Cyclin D3 promotes pancreatic beta-cell fitness and viability in a cell cycle-independent manner and is targeted in autoimmune diabetes.. Proc Natl Acad Sci U S A. 111: E3405-14.
  31. García-Arevalo M, Alonso-Magdalena P, Rebelo Dos Santos J, Quesada I, Carneiro EM, Nadal A. (2014) Exposure to Bisphenol-A during Pregnancy Partially Mimics the Effects of a High-Fat Diet Altering Glucose Homeostasis and Gene Expression in Adult Male Mice. Plos One. 9: e100214.
  32. Pizarro-Delgado J, Fasciani I, Temperan A, Romero M, González-Nieto D, Alonso-Magdalena P, Nualart-Marti A, Estil'les E, Paul DL, Martín-Del-Río R, Montanya E, Solsona C, Nadal A, Barrio LC, Tamarit-Rodríguez J. (2014) Inhibition of connexin36 hemichannels by glucose contributes to the stimulation of insulin secretion. Am J Physiol Endocrinol Metab. 306:E1354-66.
  33. Marroquí L, Alonso-Magdalena P, Merino B, Fuentes E, Nadal A, Quesada I. (2014) Nutrient regulation of glucagon secretion: involvement in metabolism and diabetes. Nutrition Research Reviews. 27: 48-62.
  34. Rafacho A, Gonçalves-Neto LM, Santos-Silva JC, Alonso-Magdalena P, Merino B, Taboga SR, Carneiro EM, Boschero AC, Nadal A, Quesada I. (2014) Pancreatic alpha-cell dysfunction contributes to the disruption of glucose homeostasis and compensatory insulin hypersecretion in glucocorticoid-treated rats. PLoS One. 9: e93531.
  35. Nadal A. (2013) Linking intermittent hypoxia, sympathetic response and metabolic disturbances. Acta Physiol (Oxf). doi: 10.1111/apha.12137.
  36. Vieira E, Marroquí L, Figueroa ALC, Merino B, Fernández Ruiz R, Nadal A, Burris T, Gomis R, Quesada I. (2013) Involvement of the clock gene Rev-erb alpha in the regulation of glucagon secretion in pancreatic alpha-cells. Plos One. 8(7): e69939.
  37. Gonzalez A, Merino B, Marroqui L, Ñeco P, Alonso-Magdalena P, Vieira E, Caballero-Garrido E, Soriano S, Gomis R, Nadal A, Quesada I. (2013) Insulin hypersecretion in islets from diet-induced hyperinsulinemic female obese mice is associated to several functional adaptations in individual beta-cells. Endocrinology. 154:3515-3524.
  38. Nadal A. (2013) Obesity: Fat from plastics? Linking bisphenol A exposure and obesity.. Nature Review Endocrinology. 9:9-10.
  39. Alonso-Magdalena P, Ropero AB, Garcia-Arevalo M, Soriano S, Quesada I, Muhammed SJ, Salehi A, Gustafsson JA, Nadal A. (2013) Antidiabetic actions of an ERβ selective agonist. Diabetes. 62:2015-2025.